Evaluation of Gastroprotective Effect of Betalain-Rich Ethanol Extract from Opuntia stricta var. Dillenii Employing an In Vivo Rat Model

The goal of this study is to investigate the antiulcer effects betalain-rich extract (BRE). Gastric ulcer was induced by administration ethanol gastric gavage route. This showed that supplementation BRE from pulp and peel at 800 mg/kg rats with ethanol-induced gastric-ulcer significantly reduced volume secretion (VGS) 35% ( p = 0.001 ) 34% id="M2"> 0.0009 ), index (UI) 41% id="M3"> 68% id="M4"> 0.0008 curative radio (CR) 68%, respectively, as compared untreated ulcer. In addition, dose attenuates variation in pH juice id="M5"> 0.008 id="M6"> its total acidity (TA) id="M7"> id="M8"> ). effect confirmed macroscopic histological evaluation. Furthermore, attenuated ulcer-induced stress oxidants rats’ stomachs a significant decrease lipid peroxidation rate id="M9"> 0.007 id="M10"> LDH activity id="M11"> 0.01 id="M12"> potential increase superoxide dismutase (SOD) id="M13"> id="M14"> glutathione peroxidase (GPX) id="M15"> 0.006 id="M16"> catalase (CAT) id="M17"> id="M18"> Conclusion. Therefore, shows for first time BRE, natural colorant O. stricta, efficient amelioration stomach inflammation.